Pharmaceutical-Grade DHEA 25 mg
plus Supportive Herbs Ginseng Wild Yam Root and Yucca
We're sorry! This item is discontinued and no longer available.
For convenient supplementation, pharmaceutical-grade DHEA - 25 mg. formulated in a supportive natural nutritional herbal base including Wild Yam Root, Korean Ginseng Root and Yucca Extract per easy-to-take tablet.
This product is formulated without added sugar, salt, starch, wheat, corn, yeast, soy derivatives, artificial colorings, flavorings or preservatives.
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DHEA Supplementation May Improve Midlife Depression
Recent research from the National Institute of Mental Health (NIMH), a branch of the National Institutes of Health (NIH), has found DHEA supplementation may be an effective treatment of midlife onset depression. The double blind, randomized, placebo-controlled treatment study was published in the February issue of Archives of General Psychiatry, an American Medical Association (AMA) journal. DHEA (dehydroepiandrosterone) is defined as an adrenal androgen and neurosteroid, classified as an over-the-counter (OTC) hormone therapy supplement.
A research team from the Behavioral Endocrinology branch of NIMH studied 23 men and 23 women aged 45 to 65 with midlife onset of depression of moderate severity. The subjects were given either six weeks or DHEA therapy – 90 mg. for the first three weeks and 450 mg. for the second three weeks – or six weeks of a placebo treatment. Researchers evaluated subjects every three and six weeks using the Hamilton Depression Scale (HDS), Center for Epidemiological Studies Depression Scale and the Derogatis Interview for Sexual Functioning Scale. They recorded a 50-percent or more reduction of depression, relative to baseline HDS score in 23 patients after DHEA supplementation. The scientists also noted six weeks of DHEA treatment was positively associated with significant improvements in Derogatis scores relative to baseline and placebo conditions.
The study authors wrote...”In the 50 percent of depressed outpatients who do not respond to first-line antidepressant treatment, or in those unwilling to take traditional antidepressants, DHEA may have a useful role in the treatment of mild to moderately severe midlife-onset major and minor depression.”
DHEA...A Naturally Produced Hormone Involved in Building Immunity, Lowering Fat Mass and Increasing Testosterone Levels
Dehydroepiandrosterone (DHEA) is one of the natural hormones produced in the body by the adrenal glands. It circulates in the bloodstream as DHEA- sulfate (DHEAS) and is converted as needed into other hormones. Significant levels of DHEA do not appear in food, and therefore dietary supplementation may be beneficial because some people may not synthesize enough DHEA.. DHEA levels typically peak in early adulthood. By the age of 60, DHEA levels are only about 5-15% of what they were at their peak at younger ages.
Supplementation with DHEA has resulted in increased levels of testosterone and androstenedione. The conversion of DHEA into testosterone may account for the fact that low blood levels of DHEA have been reported in some men with erectile dysfunction.
Some clinical trials have found that DHEA supplementation lowers fat mass without reducing total body weight. DHEA also helps build immunity. In a recent study, a group of elderly men withlow DHEA levels who were given 50mg of DHEA per day for 20 weeks experienced a significant activation of immune function.
DHEA may play an important role in protecting against depression. After six months using 50mg DHEA per day, “a remarkable increase in perceived physical and psychological well-being” was reported in both men and women in one double-blind trial. In another double-blind trial, after only six weeks of taking DHEA at levels up to 90mg per day, at least 50% reduction in depression was seen in 5 of 11 participants.
DHEA... Valuable Hormone Supplement For Men
A Naturally Produced Hormone Involved in Building Immunity, Lowering Fat Mass and Increasing Testosterone Levels
Dehydroepiandrosterone (DHEA) is one of the natural hormones produced in the body by the adrenal glands.
It circulates in the bloodstream as DHEA- sulfate (DHEAS) and is converted as needed into other hormones. Significant levels of DHEA do not appear in food, and therefore dietary supplementation may be beneficial because some people may not synthesize enough DHEA.. DHEA levels typically peak in early adulthood. By the age of 60, DHEA levels are only about 5-15% of what they were at their peak at younger ages.
Supplementation with DHEA has resulted in increased levels of testosterone and androstenedione. The conversion of DHEA into testosterone may account for the fact that low blood levels of DHEA have been reported in some men with erectile dysfunction. Thus, daily supplementation may be beneficial.
Some clinical trials have found that DHEA supplementation lowers fat mass without reducing total body weight. DHEA also helps build immunity. In a recent study, a group of elderly men withlow DHEA levels who were given 50mg of DHEA per day for 20 weeks experienced a significant activation of immune function.
DHEA may play an important role in protecting against depression. After six months using 50mg DHEA per day, "a remarkable increase in perceived physical and psychological well-being" was reported in both men and women in one double-blind trial. In another double-blind trial, after only six weeks of taking DHEA at levels up to 90mg per day, at least 50% reduction in depression was seen in 5 of 11 participants.
Hormone Levels Contribute To Stress Resilience
It is important to understand what biological mechanisms contribute to an individual's capacity to be resilient under conditions of extreme stress, such as those regularly experienced by soldiers, police, and firefighters. Researchers from Yale University and the VA National Center for PTSD have worked closely with collaborators at the Special Forces Underwater Warfare Operations Center to study special operations soldiers enrolled in the military Combat Diver Qualification Course (CDQC).
Dehydroepiandrosterone, commonly known as DHEA, is a hormone that is secreted by the adrenal gland in response to stress. Although medical scientists have known for over a decade that DHEA provides beneficial, anti-stress effects in animals, they did not know until now whether this was also true for humans.
The scientists completed psychological and hormone assessments on a group of soldiers the day before they began the month-long CDQC, and immediately after their final pass/fail exam engaged in a highly stressful, nocturnal, underwater navigation exercise.
They found that soldiers with more DHEA performed better during the final underwater navigation exam than those with less DHEA. These findings are being published by Elsevier in the August 15th issue of Biological Psychiatry.
Underwater navigation is a task that relies on an area of the brain called the hippocampus that is very sensitive to the negative effects of stress. "Animal studies have shown that DHEA buffers against stress, in part, by modulating receptors in this region of the brain; these findings are important in understanding why and how soldiers may differ in their ability to tolerate stress and also raise the possibility that, in the future, compounds like DHEA might be used to protect military personnel from the negative impact of operational stress" explained the researchers.
Clearly, additional research is still needed but these findings are a step forward in the quest to help prevent or better treat the symptoms of stress-related disorders that these high-risk individuals experience.
Journal reference: Biological Psychiatry, Volume 66, Issue 4 (August 15, 2009)
